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Spyre Therapeutics Inc. (SYRE NASDAQ) stock market data APIs

$15.4077 -0.08(-0.5%)
as of September 18, 2025
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Spyre Therapeutics Inc. Financial Data Overview

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Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. The company was incorporated in 2013 and is based in Waltham, Massachusetts.

Prev. Close 15.4077
Open 15.324
High 15.5147
Low 15.1328
52 wk Range 10.91-40.26
Market Cap 909 M
Shares Outstanding 60 401 K
EPS -0.49
Beta 2.88

* We provide hundreds of fields of fundamental data, including EBITDA, P/E ratio, PEG ratio, trailing P/E, shareholders, insider transactions, technical metrics, dividends, splits, earnings, and more. Check out our Fundamental Data API.


ETFs with Spyre Therapeutics Inc. (top by weight)

Ticker
100-day Price Change
Weight
BTEC.SW iShares Nasdaq US Biotechnology UCITS ETF USD (Acc) USD
0.69 (10.9%)
0.09
2B70.F iShares NASDAQ US Biotechnology UCITS ETF
0.35 (6.36%)
0.09
2B70.XETRA iShares Nasdaq US Biotechnology UCITS ETF USD (Acc)
0.43 (7.8%)
0.09
IBB.US iShares Biotechnology ETF
14.92 (11.59%)
0.08
VRTGX.US Vanguard Russell 2000 Growth Index Fund Institutional Shares
46.23 (11.77%)
0.04
VTWG.US Vanguard Russell 2000 Growth Index Fund ETF Shares
30.57 (14.82%)
0.04
IWO.US iShares Russell 2000 Growth ETF
41.8 (14.82%)
0.03

* We provide detailed information about ETF constituents through our Fundamentals API for ETFs. Read the documentation to learn more.


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  • EPS/Forecast: -0.7538
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